Just as every human body starts with one cell, every healthcare advancement begins with basic science. No matter how amazing the end result is, scientific success stories generally originate with a single idea in a single lab and take decades of persistent teamwork to become something of note – if they ever even do.

Weight management medications, including Wegovy, Zepbound and Foundayo, are now available to eligible Medicare beneficiaries. Universal Images Group/Getty Images hide caption toggle caption Universal Images Group/Getty Images A Medicare pilot program for GLP-1 drugs launched Wednesday. Beneficiaries may be able to get a GLP-1 prescription for weight loss for $50 a month. It’s a notable shift for Medicare, which has long been barred from covering weight loss treatments. The drugs, such as Wegovy and Zepbound, are effective […]

Mouse lines All experiments were conducted in compliance with the Association for Assessment of Laboratory Animal Care policies and approved by the Institutional Animal Care and Use Committees of the University of Virginia, University of Washington and University of California, Irvine. Mice were housed on a 12-h:12-h light–dark (LD) cycle with food (PicoLab Rodent Diet 5053) and water provided ad libitum unless otherwise indicated. For experiments, we used 8-week or older male and female C57BL/6J mice, Glp1r-IRES-Cre […]